SKU: 39842048415

CARDARINE (GW-501516) Vloeibaar 600MG

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Description

CARDARINE (GW-501516) Vloeibaar 600MGCardarine GW 501516 Wat is GW 501516? GW 501516 is een PPAR agonist (Peroxisome Proliferator Activated Receptor), oorspronkelijk ontwikkeld door GlaxoSmithKline voor de behandeling van hyperlipidemie, obesitas, metabole disfunctie en hartziekten. De verbinding staat ook bekend als Endurobol of Cardarine, en wordt in onderzoek vaak aangeduid als een PPAR agonist. Onderzoek toont aan dat GW 501516 invloed heeft op vetzuurmetabolisme,

Cardarine GW-501516

Wat is GW-501516?

GW-501516 is een PPAR-agonist (Peroxisome Proliferator-Activated Receptor), oorspronkelijk ontwikkeld door GlaxoSmithKline voor de behandeling van hyperlipidemie, obesitas, metabole disfunctie en hartziekten. De verbinding staat ook bekend als Endurobol of Cardarine, en wordt in onderzoek vaak aangeduid als een PPARδ-agonist.

Onderzoek toont aan dat GW-501516 invloed heeft op vetzuurmetabolisme, skeletspieruithoudingsvermogen, en glucose-insulinebalans. PPARδ speelt daarnaast een rol in mitochondriale ademhaling, ontstekingsregulatie, spierherstel en keratinocytdifferentiatie (bron).

Onderzoek naar uithoudingsvermogen en vetverbranding

In een muizenstudie leidde drie weken toediening van GW-501516 tot een toename van 31,2% in loopsnelheid bij getrainde ratten en 68,6% bij ongetrainde. Na slechts één week werd al een verbetering van 48,6% waargenomen ten opzichte van de controlegroep. De combinatie van Cardarine en fysieke training leidde tot verhoogde vetzuuroxidatie en energiegebruik uit lange keten vetzuren (bron).

De activering van PPARδ beïnvloedde ook spierherprogrammering via genexpressie voor contractiele eiwitten, mitochondriale biogenese en vetverbranding.

Effecten op metabole markers en ontsteking

Bij muizen op een vetrijk dieet leidde GW-501516 tot verminderde insulineresistentie, verhoogde mitochondriale activiteit, lagere vetopslag in spieren en verlaagde glucose- en insulineniveaus (bron).

Een andere studie bij fructosegevoede ratten toonde afname van leverontstekingen en verlaging van lipogene genexpressie aan. Tegelijk werden genen die vetverbranding stimuleren verhoogd (bron).

Onderzoek bij resusapen liet verbeteringen zien in HDL, LDL, triglyceriden en insulineniveaus, wat Cardarine potentieel maakt als onderzoeksobject voor cardiovasculaire aandoeningen en metabool syndroom (bron).

🧪 Inhoud

In een flesje van 30 ml zit een oplossing van 20 mg/ml.
Het flesje bevat een glazen pipet met schaalverdeling van 0,2 ml tot 1 ml, waarmee je eenvoudig en nauwkeurig kunt doseren.

📄 Disclaimer

Dit materiaal wordt uitsluitend verkocht voor gebruik in laboratoriumonderzoek. Verkoopvoorwaarden zijn van toepassing. Niet voor menselijke consumptie, noch voor medisch, diergeneeskundig of huishoudelijk gebruik. Maak uzelf vertrouwd met onze DISCLAIMER voordat u bestelt.

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SKU: 39842048415

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4.3 ★★★★★
Based on 21 reviews
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R
Verified Purchase
Rudy Ruiz
Whiting, US
★★★★★ 5
Pomeranian perfect size
Small size perfect Pomeranian (1 yr old) she prefers over other chews - have ordered twice
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 10, 2026
C
Verified Purchase
C
Phoenix, US
★★★★★ 5
My puppies favorite bone to chew
I’ve bought at least a half a dozen of puppy bones for my doggie to try, the majority being from Nylabone, and the others from hartz. Her first bone was a pink puppy Nylabone xsmall sise. She definitely must have liked that one but unfortunately I felt like I had to take it away from her too soon, she was teething more then, but even so, thought it was unsafe when I saw little pieces come off and her trying to chew them. I really like these the best, though I don’t think I’ll be ordering any more at least not until she finishes her new ones. I don’t know what flavor she likes more, it might even be a color thing, but I think she prefers the orange ones which are peanut butter flavored. These are really ideal for toy breeds. My pup is still growing, she’s almost 7 months now, but unsure when she will stop growing, for reference she is a chocolate sable yorkiepoo, not sure of how much she weighs right now, but would estimate she weighs around 5.5-6 pounds. These are perfect for her, and I feel like they out live the other ones I’ve gotten, or she just has more interest in them. I bought a second package on subscribe and save (or possibly on my first and forgot I had a new order and didn’t return), but didn’t open the new package until recently as I felt the first pack were starting to look a bit knawed off, but in the middle there was still plenty of chew left. Oddly, she has prefered the old orange one vs the brand new orange one despite them being the exact same toy and flavor. I think she just hasn’t broken it in yet and I overloaded her with too many toys! I also got them for a great price, for some reason I noticed that the price increased nearly double of what I paid, and now they habe decreased a bit but still are about $2 more than what I paid. She loves all toys, and has many plush kinds. She still teeths, so when she is extra hyper and such, I feel like the bone helps occupy her for a moment. All in all I’d reccomend these out of any puppy bones to chew for toy breeds!
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Reviewed in the United States on April 2, 2022
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J CASSIN
Houston, US
★★★★★ 4
Nice chew toy
Puppy likes but for me to hold so she can chew is a little difficult.
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Reviewed in the United States on May 8, 2026
A
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Amazon Customer
Birmingham, US
★★★★★ 5
Love nylabones
Nylabbones did it again. The pugs love these. They're so cute and tiny. Perfect for their lithe selves. They're still safe and soft and very chewable.
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Reviewed in the United States on November 16, 2025
A
Verified Purchase
Anoni Miss
Fort Morgan, US
★★★★★ 3
Not safe, easily chewed bits off
Mixed feelings. My puppies love them and love to chew on them but also chewed the edges off pretty quickly. I had to take away the first one after only a couple days of intermittent chew so it’s really not durable or long lasting. I don’t feel this is safe for a 12 week old puppy which is super small and can be a choking hazard.
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Reviewed in the United States on October 6, 2025

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