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Description
RNA polymerase II CTD repeat YSPTSPS (phospho S2) Recombinant Rat mAb (S-R199)Product Specification Host Rat Antigen RNA polymerase II CTD repeat YSPTSPS (phospho S2) Synonyms DNA directed RNA polymerase II subunit RPB1; RNA polymerase II subunit B1; DNA directed RNA polymerase II subunit A; DNA directed RNA polymerase III largest subunit; RNA directed RNA polymerase II subunit RPB1; POLR2A Location Cytoplasm, Nucleus Accession P24928 Clone Number S R199 Antibody Type Recombinant mAb Isotype IgG1 Application WB, IHC P, ICC, IF
Product Specification
| Host | Rat |
| Antigen | RNA polymerase II CTD repeat YSPTSPS (phospho S2) |
| Synonyms | DNA-directed RNA polymerase II subunit RPB1; RNA polymerase II subunit B1; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase III largest subunit; RNA-directed RNA polymerase II subunit RPB1; POLR2A |
| Location | Cytoplasm, Nucleus |
| Accession | P24928 |
| Clone Number | S-R199 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG1 |
| Application | WB, IHC-P, ICC, IF |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein G |
| Concentration | 0.4 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC | 1:400 | |
| ICC | 1:100 | |
| IF | 1:100 |
Background
RNA polymerase II (RNAP II and Pol II) is a multiprotein complex that transcribes DNA into precursors of messenger RNA (mRNA) and most small nuclear RNA (snRNA) and microRNA. The purified enzyme has typically 10–12 subunits (12 in humans and yeast). The subunit RPB1 contains a carboxy terminal domain (CTD) composed of up to 52 heptapeptide repeats (YSPTSPS) that are essential for polymerase activity.
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4.1 ★★★★★
Based on 1483 reviews
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Product Reviews
★★★★★ 4
Our pup loves the cronch cronch!
Style: Ball, Size: Medium (Pack of 1)
I bought our 15 month old Coton several Chuck-It toys on an Amazon deal. He is incredibly playful, mischievous, and ball/toy obsessed, especially for anything that makes noise. He can also be very destructive so I love how durable most of their products are - they’re among our longest lasting toys and worth every penny. We have yet to take them to the dog park, but they’re a perfect size for sharing in play time. And they are keeping him busy at home - that’s a good thing.
He loves investigating the crunchy-cronchy-crinkly sound which is a nice change from squeakers. It can withstand his destructive chewing well-being, gentle on his little teeth. I love that. Chuck-It is thinking outside the box with a variety of balls to keep dogs engaged! I do worry about the crinkle plastic inside because it is accessible because of the air holes and it feels a little sharp. So this will have to be an at home toy so we can monitor his play.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 28, 2026
★★★★★ 5
Great products all around
Style: Ball, Size: Medium (Pack of 2)
Any of these balls are great! My dogs love all of them. The squeaky ones are their favorite!
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Reviewed in the United States on March 12, 2026
★★★★★ 5
My dog loves it!
Style: Ball, Size: Medium (Pack of 1)
This crunch ball was a Christmas gift for my 65lbs fur baby. It’s now mid April and he still loves it. He loves running after it and chomping down on it. It is still in good shape despite all the chomping it’s gotta . I highly recommend. He goes back to this toy agin and again! Great buy.
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Reviewed in the United States on April 15, 2026
★★★★★ 5
Our first babies favorite and longest lasting ball yet and he is fixing to be 7.
Style: Ball, Size: Medium (Pack of 2), Style: Ball, Size: Medium (Pack of 2)
Toughest ball we have found yet. Our doberman loves Chuckit! Balls especially the crunch one. He spreads all the balls and toys we have bought but these lasted the longest. The crunch and the glow in the dark are usually his pick but he has several different choices.
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Reviewed in the United States on May 24, 2026
★★★★★ 5
Great treat replacing for motivated dogs!!!
Color: Yellow
i use this ball strictly for training purposes with my Aussie who is super obsessed with balls. My dog seriously loves this ball. This has taken the place of treats. When we aren’t training the ball goes in a closet. So far it’s durable enough for our training session. (If we have a good session he is rewarded with having free access to the ball for a limited time, he enjoys a little tug so I normally hold the rope and let him have at the ball) for $10 id say it’s worth it. It’s definitely not indestructible but it is cheaper for me to replace these than buying treats every week as rewards.
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Reviewed in the United States on January 17, 2026
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